The Ontario SPOR SUPPORT Unit (OSSU) is a collaboration across 12 leading Ontario health research centres. Jointly funded by the Government of Ontario and the Canadian Institutes of Health Research, the initiative engages researchers, patients, clinicians, policy-makers, industry representatives and other health system professionals to implement Canada’s Strategy for Patient-Oriented Research within Ontario. In particular, OSSU provides expertise and support to those engaged in patient-oriented research, and promotes knowledge transfer and exchange of the latest research evidence to inform and implement more effective health policy and clinical practices throughout the province.